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Transcription profiling of mouse uteri after ovariectomy and DHT treatment.

ABSTRACT: Morphogenesis of epithelial tissues relies on the precise developmental control of cell polarity and architecture. In the early Drosophila embryo, the primary epithelium forms during cellularisation, following a tightly controlled genetic programme where specific sets of genes are up-regulated. Some of them, for instance, control membrane invagination between the nuclei anchored at the apical surface of the syncytium. We study the whole genome expression profile aftre DHT treatment in the uteri of gonadectomized mouse. Experiment Overall Design: Ten 10-11 weeks old C57Bl/6 mice were gonadectomized under isoflurane-induced anesthesia and sacrified seven days after GDX. Mice were injected s.c with DHT (0.1mg/mice) or vehicle, at 0.5, 1, 3, 6, 12 or 24 h before sacrifice. Uteri was removed and pooled before total RNA extraction. Samples was hybridized to U74Av2 Genechips (Affymetrix).

ORGANISM(S): Mus musculus

SUBMITTER: Ezequiel Calvo

PROVIDER: E-GEOD-6237 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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