Gene Expression in mice liver after knockdown of Rab5
Ontology highlight
ABSTRACT:
ORGANISM(S): Mus musculus
SUBMITTER: Agapios Sachinidis
PROVIDER: E-GEOD-67227 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
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Project description:RNAi-mediated silencing of Rab5 and the consequent loss of endosomes in the mouse liver caused severe metabolic defects such as hypoglycemia, hepatomegaly, hypercholesterolemia, hyperlipidemia and glycogen accumulation. Gene expression in mice liver after knockdown of Rab5 has been performed the Mouse Genome 430 2.0 microarrays to identify biological processes and pathways affected by Rab5.
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