Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: Chad Creighton
PROVIDER: E-GEOD-70289 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Karatas Omer Faruk OF Suer Ilknur I Yuceturk Betul B Yilmaz Mehmet M Hajiyev Yusif Y Creighton Chad J CJ Ittmann Michael M Ozen Mustafa M
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 20151022 3
The cancer stem-like cells (CSLCs) are tumorigenic cells promoting initiation, progression, and spread of the tumor. Accumulating evidences suggested the presence of CSLCs in distinct tumors including laryngeal squamous cell carcinoma (LSCC). MicroRNAs have been proposed as significant regulators of carcinogenesis, and several of them have been demonstrated to have direct roles in survival of CSLCs. In this study, we aimed to explore the role of miR-145, which is downregulated in LSCC, on cancer ...[more]