Transcription profiling of rat whole lung during hantavirus infection to investigate sex specific differences

ABSTRACT: Gene expression profiles were examined in whole lung tissue collected from male and female Long-Evans rats at different time points after inoculation with Seoul virus (i.e., the species-specific hantavirus that infects Norway rats); We used microarray analyses to analyze global gene expression differences between the sexes during hantavirus infection Experiment Overall Design: Gonadally-intact male and female rats were inoculated with 10^4 pfu of Seoul virus (strain SR-11) and lung samples were collected 0, 3, 15, and 40 days post-inoculation (p.i.) to assess gene expression patterns during the acute (i.e., days 3-15 p.i.) and persistent (i.e., day 40 p.i.) phases of infection

ORGANISM(S): Rattus norvegicus

SUBMITTER: Sabra Lynn Klein 

PROVIDER: E-GEOD-7271 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress