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Circadian and feeding rhythms differentially affect rhythmic mRNA transcription and translation in mouse liver

ABSTRACT: This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

ORGANISM(S): Mus musculus

SUBMITTER: FrÃ©dÃ©ric Gachon

PROVIDER: E-GEOD-73554 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Circadian and feeding rhythms differentially affect rhythmic mRNA transcription and translation in mouse liver.

Atger Florian F Gobet Cédric C Marquis Julien J Martin Eva E Wang Jingkui J Weger Benjamin B Lefebvre Grégory G Descombes Patrick P Naef Felix F Gachon Frédéric F

Proceedings of the National Academy of Sciences of the United States of America 20151109 47

Diurnal oscillations of gene expression are a hallmark of rhythmic physiology across most living organisms. Such oscillations are controlled by the interplay between the circadian clock and feeding rhythms. Although rhythmic mRNA accumulation has been extensively studied, comparatively less is known about their transcription and translation. Here, we quantified simultaneously temporal transcription, accumulation, and translation of mouse liver mRNAs under physiological light-dark conditions and ...[more]

PMID: 26554015

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Circadian and feeding rhythms differentially affect rhythmic mRNA transcription and translation in mouse liver [RNASeq]

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