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GE/miRNA expression profile of PBMCs in healthy subjects and MS patients after extra virgin olive oil (EVOO) intake

ABSTRACT: This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

ORGANISM(S): Homo sapiens

SUBMITTER: Antonio Moschetta

PROVIDER: E-GEOD-75027 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Genes and miRNA expression signatures in peripheral blood mononuclear cells in healthy subjects and patients with metabolic syndrome after acute intake of extra virgin olive oil.

D'Amore Simona S Vacca Michele M Cariello Marica M Graziano Giusi G D'Orazio Andria A Salvia Roberto R Sasso Rosa Cinzia RC Sabbà Carlo C Palasciano Giuseppe G Moschetta Antonio A

Biochimica et biophysica acta 20160712 11

Extra virgin olive oil (EVOO) consumption has been associated with reduced cardiovascular risk but molecular mechanisms underlying its beneficial effects are not fully understood. Here we aimed to identify genes and miRNAs expression changes mediated by acute high- and low-polyphenols EVOO intake. Pre- and post-challenge gene and miRNAs expression analysis was performed on the peripheral blood mononuclear cells (PBMCs) of 12 healthy subjects and 12 patients with metabolic syndrome (MS) by using ...[more]

PMID: 27422371

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