Browse
Submit Data
Databases
API
Help

Unknown,Transcriptomics,Genomics,Proteomics

Dataset Information

35 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Gene Expression of Mexican Patients with Breast Cancer

ABSTRACT: Gene expression of tumor sample of mexican patients with breast cancer. Samples obtained from the Hospital San Jose Tec de Monterrey. The experiments were with one color per patient, gene expression profile is from a tumor sample of mexican patients with breast cancer.

ORGANISM(S): Homo sapiens

SUBMITTER: Hugo Gomez

PROVIDER: E-GEOD-75678 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

ACCESS DATA

Json Xml

Similar Datasets

Mexican Patients with Breast Cancer

Project description:This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

2015-12-04 | E-GEOD-75685 | biostudies-arrayexpress

miRNAs Expression of Mexican Patients with Breast Cancer

Project description:miRNAs expression of tumor sample of mexican patients with breast cancer. Samples obtained from the Hospital San Jose Tec de Monterrey. The experiments were with one color per patient, miRNAs expression profile is from a tumor sample of mexican patients with breast cancer.

2015-12-04 | E-GEOD-75669 | biostudies-arrayexpress

Peripheral blood gene expression as a biomarker for early detection of Alzheimerâ??s disease

Project description:To further development of our gene expression profile of Alzheimer's disease, we have employed whole genome microarray expression profiling as a discovery platform to identify genes with the potential biomarker for early disease detection Total RNA from peripheral blood cells was extracted, reverse-transcribed and labelled, then analysed for gene expression using GeneSpring GX12 (Agilent Technologies, USA). About 180 samples (AD=90, Non-demented control=90) was used for microarray analysis.

2016-08-11 | E-GEOD-85426 | biostudies-arrayexpress

Downstream genes regulated by TSHZ2 in MCF-7 cells

Project description:To clarify downstream genes regulated by TSHZ2, MCF-7 cells were lentivirally transduced by TSHZ2 and its control LacZ and served their RNA samples for gene expression analysis using AGILENT human 8x60K cDNA microarray. Array analysis of MCF-7 cells expressing either TSHZ2 or LacZ. 1 color method was employed.

2016-01-11 | E-GEOD-64351 | biostudies-arrayexpress

GLI1-regulated genes in human mammary epithelial cells and human breast cancer cells

Project description:To clarify transcriptional target genes of GLI1 in human mammary epithelial cells and breast cancer cells, primary culture cells of human mammary epithelium HMEC and breast cancer cell line MCF-7 were lentivirally transduced by either GLI1 or its control LacZ. Their RNA samples were served for expression analysis using AGILENT human 8x60K cDNA microarray. Array analysis of HMEC and MCF-7 expressing either GLI1 or LacZ. 1 color method was employed.

2015-04-28 | E-GEOD-64350 | biostudies-arrayexpress

Reproduction of reset cell

Project description:Functional-assay limitations are an emerging issue in characterizing human pluripotent stem cells (hPSCs). With rodent PSCs, chimera formation, using pre-implantation embryos, is the gold-standard assay of pluripotency. In hPSCs, this can only be monitored via teratoma formation or in vitro differentiation, as ethical concerns preclude generation of human-animal chimera. To circumvent this issue, we established a functional assay utilizing interspecific blastocyst injection and in vitro culture (interspecies in vitro chimera assay). The assay uses mouse pre-implantation embryos and human PSCs to make interspecies chimeras cultured in vitro to the early egg cylinder stage. When hiPSCs, both conventional and naive type, which called M-bM-^@M-^\reset cellM-bM-^@M-^], were injected into mouse embryos and cultured. The cells were never integrated into the epiblast of egg cylinder stage-embryo. These results suggest that hPSCs, including naM-CM-/ve type, are unable to form chimera with mouse embryo. Reset cells were converted from conventional human iPSC line PB004, and then compared their gene expression profile with or without transgene overexpression induced by doxycyclin treatment.

2015-03-10 | E-GEOD-66657 | biostudies-arrayexpress

Gene expression study in WT and NOTCH1 mutated CLL cells.

Project description:Stabilizing mutations of NOTCH1 have been identified in about 10% of chronic lymphocytic leukemia (CLL) cases at diagnosis, with a higher frequency in unmutated IGHV (IGHV-UM) CLL, chemorefractory CLL and CLL in advanced disease phases. Clinically, the presence of NOTCH1 mutations is an independent predictor of overall survival in CLL and associates with resistance to anti-Cd20 immunotherapy. The Gene Expression Profile was generated to identify the peculiar molecular signatures of NOTCH1 mutated CLL in the context of IGHV-UM CLL. Constitutive gene expression in CLL cells bearing or not NOTCH1 mutation (c.7541_7542delCT). Five samples were selected for each category (WT vs MUT).

2016-03-01 | E-GEOD-75122 | biostudies-arrayexpress

Identification of a Highly Immunogenic Mouse Breast Cancer Sub Cell Line, 4T1-S

Project description:Recently, cancer immunotherapy has been paid much attention because of its improved efficacy and low frequency of adverse effects. A mouse breast cancer cell line, 4T1, has been known as poorly immunogeneic and highly metastatic cell line. In this study, we have identified a sub cell line of 4T1, designated as 4T1-Sapporo (4T1-S), which could induce a strong immune response against the same line. When 4T1-S was subcutaneously injected, striking enlargement of draining lymph nodes and increase of activated T cells were observed. The strong immune responses could not be observed when 4T1-S was injected to nude mice, indicating that this phenomenon is mediated by T cell response. Identification of 4T1-S characteristics may help to improve immunotherapy against breast cancer. 4T1-A1, 4T1-A2, 4T1-S1, 4T1-S2

2015-11-01 | E-GEOD-71926 | biostudies-arrayexpress

Transcriptomic signatures of Auger electron radioimmunotherapy using nuclear targeting 111In-trastuzumab for potential combination therapies

Project description:The aim of this study was to identify targetable molecular signatures for enhancing the cytotoxic effects of In-111-trastuzumab-NLS using microarray technology. Changes in gene expression in SKBR3 cells untreated or treated with unlabeled or In-111-labeled antibodies for 7 days were measured. Three independent experiments in each condition were performed.

2015-09-01 | E-GEOD-67193 | biostudies-arrayexpress

Gene expression data from control and REPTOR (=CG13624) KO male adults

Project description:The aim was to identify genes whose transcription is induced or repressed by REPTOR (=CG13624) KO in Drosophila melanogaster male adults. Data are part of the manuscript REPTOR and REPTOR-BP regulate organismal metabolism and transcription downstream of mTORC1 2 biological replicates from 2 conditions: Control adult males / REPTOR KO adult males ; 4 samples

2015-04-30 | E-GEOD-64846 | biostudies-arrayexpress

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data