Unknown,Transcriptomics,Genomics,Proteomics

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Stress-dependent dynamics of chromatin remodeling in yeast: Dual roles for SWI/SNF in heat shock stress response

ABSTRACT: Total H4 and acetyl H4 IP, time course Total H4 and acetyl H4 occupancy, Snf2 occupancy, gene expression analysis Keywords: stress response, time course S cerevisiae were subjected to heat shock and stationary phase stress. The histone occupancy and H4 acetylation levels were monitored in parallel with gene expression studies, and Snf2 occupancy before and after stress.

ORGANISM(S): Saccharomyces cerevisiae

SUBMITTER: Sushma Shivaswamy

PROVIDER: E-GEOD-7665 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Stress-dependent dynamics of global chromatin remodeling in yeast: dual role for SWI/SNF in the heat shock stress response.

Shivaswamy Sushma S Iyer Vishwanath R VR

Molecular and cellular biology 20080122 7

Although chromatin structure is known to affect transcriptional activity, it is not clear how broadly patterns of changes in histone modifications and nucleosome occupancy affect the dynamic regulation of transcription in response to perturbations. The identity and role of chromatin remodelers that mediate some of these changes are also unclear. Here, we performed temporal genome-wide analyses of gene expression, nucleosome occupancy, and histone H4 acetylation during the response of yeast (Sacc ...[more]

PMID: 18212068

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Dataset Information

Stress-dependent dynamics of chromatin remodeling in yeast: Dual roles for SWI/SNF in heat shock stress response

Publications

Stress-dependent dynamics of global chromatin remodeling in yeast: dual role for SWI/SNF in the heat shock stress response.

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