Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: Venugopalan Nair
PROVIDER: E-GEOD-77668 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Nair Venugopalan D VD Nair Venugopalan D VD Ge Yongchao Y
Neuroscience letters 20160629
Molecular adaptations in the striatum mediated by dopamine (DA) denervation and/or levodopa (L-dopa) treatments have been implicated in the motor deficits found in Parkinson's disease (PD). Alterations in inflammatory response mechanisms and glutamatergic neurotransmission are reported to play important roles in mediating these changes. However, the mechanisms mediating the molecular adaptations in the striatum are not well understood. Small non-coding microRNAs (miRNAs) influence numerous biolo ...[more]