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Normal and Renal Cell Carcinoma Kidney Tissue, Human

ABSTRACT: Each total RNA sample is hybridized to two different arrays: Affymetrix U133A (GPL96) and U133B (GPL97). For most of the normal tissue samples there is a renal clear cell carcinoma sample from the same patient. There is no matching tumor sample for normal sample N1. For most of the renal clear cell carcinoma samples there is a corresponding adjacent normal tissue sample from the same patient. There are no matching normal tissue samples for C011 or C032. Keywords = kidney Keywords = renal Keywords = RCC Keywords = carcinoma Keywords = cancer Keywords: parallel sample

ORGANISM(S): Homo sapiens

SUBMITTER: Marc Lenburg

PROVIDER: E-GEOD-781 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Previously unidentified changes in renal cell carcinoma gene expression identified by parametric analysis of microarray data.

Lenburg Marc E ME Liou Louis S LS Gerry Norman P NP Frampton Garrett M GM Cohen Herbert T HT Christman Michael F MF

BMC cancer 20031127

<h4>Background</h4>Renal cell carcinoma is a common malignancy that often presents as a metastatic-disease for which there are no effective treatments. To gain insights into the mechanism of renal cell carcinogenesis, a number of genome-wide expression profiling studies have been performed. Surprisingly, there is very poor agreement among these studies as to which genes are differentially regulated. To better understand this lack of agreement we profiled renal cell tumor gene expression using ge ...[more]

PMID: 14641932

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