Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: Daisuke Okuzaki
PROVIDER: E-GEOD-79629 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Barman Soumik S Kayama Hisako H Okuzaki Daisuke D Ogino Takayuki T Osawa Hideki H Matsuno Hiroshi H Mizushima Tsunekazu T Mori Masaki M Nishimura Junichi J Takeda Kiyoshi K
International immunology 20160715 11
Inappropriate activation of T helper (Th) cells, such as Th1 and Th17 cells, is implicated in the pathogenesis of chronic inflammatory disorders including ulcerative colitis (UC). CX<sub>3</sub>CR1<sup>high</sup> macrophages contribute to intestinal homeostasis through various mechanisms in mice. However, whether mononuclear phagocytes with regulatory functions are present in the human colon is not clearly defined. We investigated whether innate myeloid cells that suppress activation of effector ...[more]