Ontology highlight
ABSTRACT:
ORGANISM(S): Schizosaccharomyces pombe
SUBMITTER: Sander Granneman
PROVIDER: E-GEOD-82326 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Lemay Jean-François JF Marguerat Samuel S Larochelle Marc M Liu Xiaochuan X van Nues Rob R Hunyadkürti Judit J Hoque Mainul M Tian Bin B Granneman Sander S Bähler Jürg J Bachand François F
Genes & development 20160701 13
Termination of RNA polymerase II (RNAPII) transcription is associated with RNA 3' end formation. For coding genes, termination is initiated by the cleavage/polyadenylation machinery. In contrast, a majority of noncoding transcription events in Saccharomyces cerevisiae does not rely on RNA cleavage for termination but instead terminates via a pathway that requires the Nrd1-Nab3-Sen1 (NNS) complex. Here we show that the Schizosaccharomyces pombe ortholog of Nrd1, Seb1, does not function in NNS-lik ...[more]