Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: Rogier Versteeg
PROVIDER: E-GEOD-8840 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Genes, chromosomes & cancer 20090601 6
Rhabdomyosarcomas (RMS) are the most common pediatric soft tissue sarcomas. They resemble developing skeletal muscle and are histologically divided into two main subtypes; alveolar and embryonal RMS. Characteristic genomic aberrations, including the PAX3- and PAX7-FOXO1 fusion genes in alveolar cases, have led to increased understanding of their molecular biology. Here, we determined the effect of genomic copy number on gene expression levels through array comparative genomic hybridization (CGH) ...[more]