Skeletal muscle cell fusion time course
Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: Ellen Sterrenburg
PROVIDER: E-GEOD-906 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Publications
Large-scale gene expression analysis of human skeletal myoblast differentiation.
Sterrenburg Ellen E Turk Rolf R 't Hoen Peter A C PA van Deutekom Judith C T JC Boer Judith M JM van Ommen Gert-Jan B GJ den Dunnen Johan T JT
Neuromuscular disorders : NMD 20040901 8-9
To study pathways involved in human skeletal myogenesis, we profiled gene expression in human primary myoblast cells derived from three individuals using both oligonucleotide and cDNA microarrays. Following stringent statistical testing (false-positive rate 0.4%), we identified 146 genes differentially expressed over time. Interestingly, 86 of these genes have not been reported to be involved in myogenesis in mouse cell lines. This demonstrates the additional value of human primary cell cultures ...[more]
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