Gene expression variation in Y-chromosome substitution lines of Drosophila melanogaster
Ontology highlight
ABSTRACT:
ORGANISM(S): Drosophila melanogaster
SUBMITTER: Bernardo Lemos
PROVIDER: E-GEOD-9457 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Publications
Epigenetic effects of polymorphic Y chromosomes modulate chromatin components, immune response, and sexual conflict.
Lemos Bernardo B Branco Alan T AT Hartl Daniel L DL
Proceedings of the National Academy of Sciences of the United States of America 20100823 36
Genetic conflicts between sexes and generations provide a foundation for understanding the functional evolution of sex chromosomes and sexually dimorphic phenotypes. Y chromosomes of Drosophila contain multi-megabase stretches of satellite DNA repeats and a handful of protein-coding genes that are monomorphic within species. Nevertheless, polymorphic variation in heterochromatic Y chromosomes of Drosophila result in genome-wide gene expression variation. Here we show that such naturally occurrin ...[more]
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