Ontology highlight
ABSTRACT:
ORGANISM(S): Streptomyces coelicolor
SUBMITTER: Emma Laing
PROVIDER: E-MAXD-46 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Genome biology 20090116 1
<h4>Background</h4>DNA microarrays are a key resource for global analysis of genome content, gene expression and the distribution of transcription factor binding sites. We describe the development and application of versatile high density ink-jet in situ-synthesized DNA arrays for the G+C rich bacterium Streptomyces coelicolor. High G+C content DNA probes often perform poorly on arrays, yielding either weak hybridization or non-specific signals. Thus, more than one million 60-mer oligonucleotide ...[more]