Unknown,Transcriptomics,Genomics,Proteomics

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Measurement of mRNA decay in exponentially growing cultures of the extremely halophilic euryarchaeon Halobacterium salinarum NRC-1 after blocking transcription with actinomycin D


ABSTRACT: mRNA half-lives in exponentially growing cultures of the extremely halophilic euryarchaeon Halobacterium salinarum NRC-1

INSTRUMENT(S): GenePix 4000A [Axon Instruments]

ORGANISM(S): Halobacterium salinarum

SUBMITTER: Sonja Hundt 

PROVIDER: E-MEXP-1088 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Publications

Global analysis of mRNA decay in Halobacterium salinarum NRC-1 at single-gene resolution using DNA microarrays.

Hundt Sonja S   Zaigler Alexander A   Lange Christian C   Soppa Jörg J   Klug Gabriele G  

Journal of bacteriology 20070720 19


RNA degradation is an important factor in the regulation of gene expression. It allows organisms to quickly respond to changing environmental conditions by adapting the expression of individual genes. The stability of individual mRNAs within an organism varies considerably, contributing to differential amounts of proteins expressed. In this study we used DNA microarrays to analyze mRNA degradation in exponentially growing cultures of the extremely halophilic euryarchaeon Halobacterium salinarum  ...[more]

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