Unknown,Transcriptomics,Genomics,Proteomics

Dataset Information

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Comparative genomic hybridization of yeast to determine size characteristics of yeast haploid deletion strains separated by elutriation


ABSTRACT: Determination of size characteristics of pools of yeast haploid deletion strains by elutriation and barcode analysis.

INSTRUMENT(S): GenePix 4000B [Axon Instruments], ScanArray [PerkinElmer]

ORGANISM(S): Saccharomyces cerevisiae

SUBMITTER: Chi-Yip Ho 

PROVIDER: E-MEXP-1200 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Publications

Systematic validation and atomic force microscopy of non-covalent short oligonucleotide barcode microarrays.

Cook Michael A MA   Chan Chi-Kin CK   Jorgensen Paul P   Ketela Troy T   So Daniel D   Tyers Mike M   Ho Chi-Yip CY  

PloS one 20080206 2


<h4>Background</h4>Molecular barcode arrays provide a powerful means to analyze cellular phenotypes in parallel through detection of short (20-60 base) unique sequence tags, or "barcodes", associated with each strain or clone in a collection. However, costs of current methods for microarray construction, whether by in situ oligonucleotide synthesis or ex situ coupling of modified oligonucleotides to the slide surface are often prohibitive to large-scale analyses.<h4>Methodology/principal finding  ...[more]