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Transcription profiling of human enterocytes cultured with different dietary lipids

ABSTRACT: The present study aimed to identify the specific impact of dietary lipids-containing micelles on gene expression in enterocytes.

ORGANISM(S): Homo sapiens

SUBMITTER: Dominique Simon

PROVIDER: E-MEXP-1446 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Transcriptome response of enterocytes to dietary lipids: impact on cell architecture, signaling, and metabolism genes.

Béaslas Olivier O Torreilles François F Casellas Pierre P Simon Dominique D Fabre Gérard G Lacasa Michel M Delers François F Chambaz Jean J Rousset Monique M Carrière Véronique V

American journal of physiology. Gastrointestinal and liver physiology 20080828 5

Intestine contributes to lipid homeostasis through the absorption of dietary lipids, which reach the apical pole of enterocytes as micelles. The present study aimed to identify the specific impact of these dietary lipid-containing micelles on gene expression in enterocytes. We analyzed, by microarray, the modulation of gene expression in Caco-2/TC7 cells in response to different lipid supply conditions that reproduced either the permanent presence of albumin-bound lipids at the basal pole of ent ...[more]

PMID: 18755805

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