Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: ILIAS KRAMBOVITIS
PROVIDER: E-MEXP-1586 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Morou Antigone K AK Porichis Filippos F Krambovitis Elias E Sourvinos George G Spandidos Demetrios A DA Zafiropoulos Alexandros A
Journal of translational medicine 20110924
<h4>Background</h4>The asymptomatic phase of HIV-1 infection is characterized by a progressive depletion of uninfected peripheral effector/memory CD4+ T cells that subsequently leads to immune dysfunction and AIDS symptoms. We have previously demonstrated that the presence of specific gp120/V3 peptides during antigen presentation can modify the activation of normal T-cells leading to altered immune function. The aim of the present study was to map the specific transcriptional profile invoked by ...[more]