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Comparative genomic hybridization of Bordetella pertussis clinical isoltates circultating in Senegal

ABSTRACT: Genomic content of Bordetella pertussis clinical isolates circulating in Senegal

ORGANISM(S): Bordetella pertussis

SUBMITTER: Valerie Bouchez

PROVIDER: E-MEXP-1674 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Genomic analysis and comparison of Bordetella pertussis isolates circulating in low and high vaccine coverage areas.

Njamkepo Elisabeth E Cantinelli Thomas T Guigon Ghislaine G Guiso Nicole N

Microbes and infection 20081017 14-15

The aim of this study was to analyze Bordetella pertussis isolates circulating, between 1991 and 1995, in Niakhar, Senegal area where the pertussis vaccination coverage was low and to compare them with those circulating in France, before and after introduction of generalized pertussis vaccination for toddlers in 1959. We carried out bacteriological analyses, typing, genotyping and DNA microarray analyses. We found that the isolates circulating in Senegal between 1991 and 1995 are part of the sam ...[more]

PMID: 18977453

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