Unknown,Transcriptomics,Genomics,Proteomics

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Transcription profiling of Arabidopsis wild-type and atbzip60 mutant plants in response to the ER stress inducer tunicamycin


ABSTRACT: AtbZIP60 is one of the transcription factors involved in the endoplasmic reticulum (ER) stress response in Arabidopsis. To identify genes under the control of AtbZIP60 during ER stress, we compared the genome-wide expression profiles of wild-type and atbzip60 mutant plants in response to the ER stress inducer tunicamycin.

ORGANISM(S): Arabidopsis thaliana

SUBMITTER: Yuji Iwata 

PROVIDER: E-MEXP-1753 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Publications

Arabidopsis bZIP60 is a proteolysis-activated transcription factor involved in the endoplasmic reticulum stress response.

Iwata Yuji Y   Fedoroff Nina V NV   Koizumi Nozomu N  

The Plant cell 20081118 11


Proteins synthesized in the endoplasmic reticulum (ER) of eukaryotic cells must be folded correctly before translocation out of the ER. Disruption of protein folding results in the induction of genes for ER-resident chaperones, for example, BiP. This phenomenon is known as the ER stress response. We report here that bZIP60, an Arabidopsis thaliana basic leucine zipper (bZIP) transcription factor with a transmembrane domain, is involved in the ER stress response. When compared with wild-type Arab  ...[more]

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