Project description:Effects of genetic modification of trans-acting transcription factors and a chromatin remodeler on noncoding RNA transcription and trans-acting factor binding at loci in yeast.
Project description:In order to identify the subset of genes directly regulated by Foxa2 in the liver, we performed genome-wide location analysis. Chromatin immunoprecipitation (ChIP) samples from livers of wild type and Foxa2 liver-conditional null mice (Foxa2loxP/loxPAlfp.Cre) were hybridized to a mouse enhancer/promoter microarray with more than 36,000 elements (BCBCPromChip 5). This analysis identified 574 enhancer and promoter regions, corresponding to 484 unique genes, as occupied by Foxa2 in the adult liver.
Project description:Chromatin immunoprecipitation and hybridization to a chromosome-wide DNA tiling array (ChIP-chip)was performed to compare the distribution of H3K4me2 in nrpd1a-4_nrpd1b-11 double mutant and in the wild type. Experiments were done using two independent biological replicates.<br><br>
Project description:Chromatin immunoprecipitation and hybridization to a chromosome-wide DNA tiling array (ChIP-chip)was performed to compare the distribution pattern of H3K9me2 between nrpd1a-4_nrpd1b-11 and wild type. Experiments were done using two independent biological replicates.<br>
Project description:Transcriptome analysis in nodules of Medicago truncatula with customn 2.3K cDNA arrays.<br><br>Study of different nodule developmental stages in wild type.<br><br>Study of various mutants forming non-functional nodules.
Project description:full human genome expression microarrays were used to analysis of gene expression profiles upon the induction of MSC osteogenic differentiation.
Project description:Comparison of the transcriptome of nrpd1a-4_nrpd1b-11 mutant and the wild type. Experiments were done using two independent biological replicates.<br><br>