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Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

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Transcription profiling of human heart characterizing the progression of heart failure in patients with aortic valve stenosis

ABSTRACT: Myocardial left ventricular biopsies from male patients (n=6) with isolated aortic stenosis and pronounced left ventricular hypertrophy undergoing aortic valve replacement were harvested either from hearts with normal ejection fraction (EF,>50%) or with low EF (<30%). Biopsies were further obtained from non-hypertrophied hearts with normal EF (>60%) from coronary artery disease patients undergoing coronary artery bypass graft surgery (n=3). Total RNA isolated from biopsies was analyzed using Affymetrix HG-U133A and U133B GeneChip sets.

ORGANISM(S): Homo sapiens

DISEASE(S): aortic valve stenosis

SUBMITTER: Wolfgang Schmidt

PROVIDER: E-MEXP-2296 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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