Unknown,Transcriptomics,Genomics,Proteomics

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Transcription profiling by array of Burkholderia cenocepacia J2315 grown to mid-stationary phase in basal salt medium with glucose or glycerol substrates


ABSTRACT: B. cenocepacia J2315 was grown to mid-stationary phase in basal salt medium with two different substrates: 20 mM glucose or 40 mM glycerol. Cells were harvested after 30 hours incubation at 37 degrees centigrade.
The expression profile was compared to cells grown on the same medium and harvested in mid-log phase.

ORGANISM(S): Burkholderia cenocepacia

SUBMITTER: Andrea Sass 

PROVIDER: E-MEXP-2772 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Publications

The unexpected discovery of a novel low-oxygen-activated locus for the anoxic persistence of Burkholderia cenocepacia.

Sass Andrea M AM   Schmerk Crystal C   Agnoli Kirsty K   Norville Phillip J PJ   Eberl Leo L   Valvano Miguel A MA   Mahenthiralingam Eshwar E  

The ISME journal 20130314 8


Burkholderia cenocepacia is a Gram-negative aerobic bacterium that belongs to a group of opportunistic pathogens displaying diverse environmental and pathogenic lifestyles. B. cenocepacia is known for its ability to cause lung infections in people with cystic fibrosis and it possesses a large 8 Mb multireplicon genome encoding a wide array of pathogenicity and fitness genes. Transcriptomic profiling across nine growth conditions was performed to identify the global gene expression changes made w  ...[more]

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