Ontology highlight
ABSTRACT:
ORGANISM(S): Mus musculus
SUBMITTER: Donald Dunbar
PROVIDER: E-MEXP-3091 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Morton Nicholas M NM Nelson Yvonne B YB Michailidou Zoi Z Di Rollo Emma M EM Ramage Lynne L Hadoke Patrick W F PW Seckl Jonathan R JR Bunger Lutz L Horvat Simon S Kenyon Christopher J CJ Dunbar Donald R DR
PloS one 20110907 9
<h4>Background</h4>Obesity and metabolic syndrome results from a complex interaction between genetic and environmental factors. In addition to brain-regulated processes, recent genome wide association studies have indicated that genes highly expressed in adipose tissue affect the distribution and function of fat and thus contribute to obesity. Using a stratified transcriptome gene enrichment approach we attempted to identify adipose tissue-specific obesity genes in the unique polygenic Fat (F) m ...[more]