Dataset Information
Transcriptional profile of peripheral blood mononuclear cells PBMC from type 1 Diabetes Mellitus Patients
Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
DISEASE(S): controled disease patient
SUBMITTER: Geraldo Passos
PROVIDER: E-MEXP-3348 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Publications
Integrative analysis of the transcriptome profiles observed in type 1, type 2 and gestational diabetes mellitus reveals the role of inflammation.
BMC medical genomics 20140523
<h4>Background</h4>Type 1 diabetes (T1D) is an autoimmune disease, while type 2 (T2D) and gestational diabetes (GDM) are considered metabolic disturbances. In a previous study evaluating the transcript profiling of peripheral mononuclear blood cells obtained from T1D, T2D and GDM patients we showed that the gene profile of T1D patients was closer to GDM than to T2D. To understand the influence of demographical, clinical, laboratory, pathogenetic and treatment features on the diabetes transcript ...[more]
