Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

Dataset Information

Novel biomarker combination improves the diagnosis of serious bacterial infections in Malawian children

ABSTRACT: We aimed to discover a combination of reliable and functionally important biomarkers of severe bacterial infection (SBI) using transcriptomics, and to evaluate their clinical validity.

ORGANISM(S): Homo sapiens

SUBMITTER: Fiona Marriage

PROVIDER: E-MEXP-3567 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Publications

Novel biomarker combination improves the diagnosis of serious bacterial infections in Malawian children.

Irwin Adam D AD Marriage Fiona F Mankhambo Limangeni A LA Jeffers Graham G Kolamunnage-Dona Ruwanthi R Guiver Malcolm M Denis Brigitte B Molyneux Elizabeth M EM Molyneux Malcolm E ME Day Philip J PJ Carrol Enitan D ED

BMC medical genomics 20120504

<h4>Background</h4>High throughput technologies offer insight into disease processes and heightens opportunities for improved diagnostics. Using transcriptomic analyses, we aimed to discover and to evaluate the clinical validity of a combination of reliable and functionally important biomarkers of serious bacterial infection (SBI).<h4>Methods</h4>We identified three previously reported biomarkers of infection (neutrophil gelatinase-associated lipocalin (NGAL), granulysin and resistin) and measur ...[more]

PMID: 22559298

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Dataset Information

Novel biomarker combination improves the diagnosis of serious bacterial infections in Malawian children

Publications

Novel biomarker combination improves the diagnosis of serious bacterial infections in Malawian children.

Similar Datasets

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