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Transcription profiling of equine fibroblasts transformed with Bovine Paillomarvirus type1 experimentally or from explanted sarcoids compared to control fibroblasts

ABSTRACT: Bovine Papillomavirus type 1 (BPV-1) and less commonly BPV-2 are associated with the pathogenesis of common equine skin tumours termed sarcoids. In an attempt to understand the mechanisms by which BPV-1 induces sarcoids, we used gene expression profiling as a screening tool to identify candidates genes implicated in disease pathogenesis. Gene expression profiles of equine fibroblasts transformed by BPV-1 either experimentally or from explanted tumours were compared with control equine fibroblasts to identify genes associated with expression of BPV-1.

ORGANISM(S): Equus caballus

DISEASE(S): normal

SUBMITTER: Lesley Nicolson

PROVIDER: E-MEXP-1658 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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