Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
DISEASE(S): Marsh 3
SUBMITTER: Frank Holstege
PROVIDER: E-MEXP-42 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Diosdado B B Wapenaar M C MC Franke L L Duran K J KJ Goerres M J MJ Hadithi M M Crusius J B A JB Meijer J W R JW Duggan D J DJ Mulder C J J CJ Holstege F C P FC Wijmenga C C
Gut 20040701 7
<h4>Background and aims</h4>The causative molecular pathways underlying the pathogenesis of coeliac disease are poorly understood. To unravel novel aspects of disease pathogenesis, we used microarrays to determine changes in gene expression of duodenal biopsies.<h4>Methods</h4>cDNA microarrays representing 19 200 genes were used to compare gene expression profiles of duodenal biopsies from 15 coeliac disease patients with villous atrophy (Marsh III) and seven control individuals with normal biop ...[more]