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Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

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Transcription profiling of two populations of non-hematopoetic stem cells (MSC and MAPC) isolated from human bone marrow.

ABSTRACT: Compare the behaviour of two populations of non-hematopoetic stem cells (MSC and MAPC) isolated from human bone marrow. The effect of culture conditions on the behaviour of MSC was also characterised by isolating MSC and then culturing the cells for 96h in MAPC growth conditions

ORGANISM(S): Homo sapiens

SUBMITTER: Chris Boshoff

PROVIDER: E-MEXP-466 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Validation of COL11A1/procollagen 11A1 expression in TGF-β1-activated immortalised human mesenchymal cells and in stromal cells of human colon adenocarcinoma.

Galván José A JA García-Martínez Jorge J Vázquez-Villa Fernando F García-Ocaña Marcos M García-Pravia Carmen C Menéndez-Rodríguez Primitiva P González-del Rey Carmen C Barneo-Serra Luis L de los Toyos Juan R JR

BMC cancer 20141123

<h4>Background</h4>The human COL11A1 gene has been shown to be up-regulated in stromal cells of colorectal tumours, but, so far, the immunodetection of procollagen 11A1, the primary protein product of COL11A1, has not been studied in detail in human colon adenocarcinomas. Some cancer-associated stromal cells seem to be derived from bone marrow mesenchymal cells; the expression of the COL11A1 gene and the parallel immunodetection of procollagen 11A1 have not been evaluated in these latter cells, ...[more]

PMID: 25417197

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