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Transcription profiling of Pseudomonas putida strains with wild type and inactivated cyoB alleles

ABSTRACT: Transcriptome comparison of two isogenic strains, one with a wild type cyoB allele and another with an inactivated cyoB allele

INSTRUMENT(S): ScanArray Lite [PerkinElmer]

ORGANISM(S): Pseudomonas putida

SUBMITTER: Fernando Rojo

PROVIDER: E-MEXP-639 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Inactivation of the Pseudomonas putida cytochrome o ubiquinol oxidase leads to a significant change in the transcriptome and to increased expression of the CIO and cbb3-1 terminal oxidases.

Morales Gracia G Ugidos Ana A Rojo Fernando F

Environmental microbiology 20061001 10

Pseudomonas putida KT2440 contains a branched aerobic respiratory chain with several terminal oxidases. Inactivation of the cyo terminal ubiquinol oxidase has little effect on growth rate but is known to relieve the inhibition by global control that modulates induction of genes required to assimilate alkanes in cells growing in the presence of preferred carbon sources. We show that inactivation of other terminal oxidases has no effect on regulation of the alkane degradation pathway, which points ...[more]

PMID: 16958757

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