Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

Dataset Information

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Transcription profiling of Pseudomonas putida strains with wild type and inactivated vacB alleles


ABSTRACT: Transcriptome comparison of two isogenic strains, one with a wild type vacB allele and another with an inactivated vacB allele

INSTRUMENT(S): ScanArray Lite [PerkinElmer]

ORGANISM(S): Pseudomonas putida

SUBMITTER: Pilar Fonseca 

PROVIDER: E-MEXP-1440 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Publications

Genomic analysis of the role of RNase R in the turnover of Pseudomonas putida mRNAs.

Fonseca Pilar P   Moreno Renata R   Rojo Fernando F  

Journal of bacteriology 20080718 18


RNase R is a 3'-5' highly processive exoribonuclease that can digest RNAs with extensive secondary structure. We analyzed the global effect of eliminating RNase R on the Pseudomonas putida transcriptome and the expression of the rnr gene under diverse conditions. The absence of RNase R led to increased levels of many mRNAs, indicating that it plays an important role in mRNA turnover. ...[more]

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