Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

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Transcription profiling of Pseudomonas putida wild type cells and lexA1 and lexA2 mutants after treatment with mitomcin C

ABSTRACT: The experiment try to elucidate the analysis of the genetic composition of P. putida lexA1 and lexA2 regulons in order to determine the possible relationships and overlaps between both networks. Gene expression patterns in DNA-damaged wild-type cells of P. putida, as well as in its lexA1 and lexA2 mutant derivatives, have been determined

INSTRUMENT(S): ScanArray 4000 [PerkinElmer]

ORGANISM(S): Pseudomonas putida

SUBMITTER: Susana Campoy 

PROVIDER: E-MEXP-1187 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Publications

Cohabitation of two different lexA regulons in Pseudomonas putida.

Abella Marc M   Campoy Susana S   Erill Ivan I   Rojo Fernando F   Barbé Jordi J  

Journal of bacteriology 20071012 24

In contrast to the vast majority of the members of the domain Bacteria, several Pseudomonas and Xanthomonas species have two lexA genes, whose products have been shown to recognize different LexA binding motifs, making them an interesting target for studying the interplay between cohabiting LexA regulons in a single species. Here we report an analysis of the genetic composition of the two LexA regulons of Pseudomonas putida KT2440 performed with a genomic microarray. The data obtained indicate t  ...[more]

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