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Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

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Transcription profiling of human grade II gliomas of three hystological subtypes

ABSTRACT: Gene expression profiling of 23 grade II gliomas of different histological subtype. Analyses was done on 9 astrocytomas, 8 oligoastrocytomas and 6 oligodendrogliomas.

INSTRUMENT(S): ScanArray 5000 [PerkinElmer]

ORGANISM(S): Homo sapiens

DISEASE(S): Oligodendroglioma

SUBMITTER: Daniel Hägerstrand

PROVIDER: E-MEXP-938 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Gene expression analyses of grade II gliomas and identification of rPTPbeta/zeta as a candidate oligodendroglioma marker.

Hägerstrand Daniel D Smits Anja A Eriksson Anna A Sigurdardottir Sunna S Olofsson Tommie T Hartman Magdalena M Nistér Monica M Kalimo Hannu H Ostman Arne A

Neuro-oncology 20071114 1

Grade II gliomas are morphologically and clinically heterogeneous tumors for which histopathological typing remains the major tool for clinical classification. To what extent the major histological subtypes - astrocytomas, oligodendrogliomas, and oligoastrocytomas - constitute true biological entities is largely unresolved. Furthermore, morphological classification is often ambiguous and would be facilitated by specific subtype markers. In this study, 23 grade II gliomas were expression-profiled ...[more]

PMID: 18003890

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