Ontology highlight
ABSTRACT:
ORGANISM(S): Mus musculus
SUBMITTER: Matthew Trotter
PROVIDER: E-MEXP-955 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Brons I Gabrielle M IG Smithers Lucy E LE Trotter Matthew W B MW Rugg-Gunn Peter P Sun Bowen B Chuva de Sousa Lopes Susana M SM Howlett Sarah K SK Clarkson Amanda A Ahrlund-Richter Lars L Pedersen Roger A RA Vallier Ludovic L
Nature 20070627 7150
Although the first mouse embryonic stem (ES) cell lines were derived 25 years ago using feeder-layer-based blastocyst cultures, subsequent efforts to extend the approach to other mammals, including both laboratory and domestic species, have been relatively unsuccessful. The most notable exceptions were the derivation of non-human primate ES cell lines followed shortly thereafter by their derivation of human ES cells. Despite the apparent common origin and the similar pluripotency of mouse and hu ...[more]