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RNA-seq of rs2280381-containing region knock out clone in U937

ABSTRACT: rs2280381 is an autoimmune disease susceptible loci, which have be reported to be associated with SLE, RA and SSc.Genetic and epigenomic analysis indicate that rs2280381-containing region is an enhancer region in monocyte. To test the function and regulated genes of rs228381-containing region, we deleted rs2280381 ~120bp sequence in U-937 cells, and performed the RNA-seq to detect the gene expression profiles.

INSTRUMENT(S): HiSeq X Ten

ORGANISM(S): Homo sapiens

SUBMITTER: Tian Zhou

PROVIDER: E-MTAB-10126 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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