Ontology highlight
ABSTRACT:
INSTRUMENT(S): Illumina NovaSeq 6000
ORGANISM(S): Mus musculus
SUBMITTER: Christophe Desmet
PROVIDER: E-MTAB-10188 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Van Hulst Glenn G Jorssen Joseph J Jacobs Nathalie N Henket Monique M Louis Renaud R Schleich Florence F Bureau Fabrice F Desmet Christophe J CJ
The European respiratory journal 20220317 3
Neutralising antibodies against the cytokine interleukin (IL)5 have become widely used for the control of severe eosinophilic asthma. Remarkably, patients receiving neutralising anti-IL5 biological therapies retain a very stable population of residual blood eosinophils. Whether these residual eosinophils are endowed with particular biological activity has not yet been studied, but is of importance in predicting potential long-term effects of IL5 neutralisation in patients. To tackle the effect o ...[more]