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Methylation arrays (MethylationEPIC) of peripheral blood of individuals with evolving dementia

ABSTRACT: DNA methylation changes have been associated to dementia and cognitive decline. However, it is not clear if these changes arise before or during the onset of the pathologies. Here, using Illumina's MethylationEPIC array technology, we have profiled the methylomes of elderly, cognitively healthy individuals which go on to develop dementia or stay cognitively healthy. The subjects are profiled at a pre-diagnosis stage and at 4 year follow-up post-diagnosis.

ORGANISM(S): Homo sapiens

SUBMITTER: Mario Fraga F.

PROVIDER: E-MTAB-10600 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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