Unknown,Transcriptomics,Genomics,Proteomics

Dataset Information

Gene expression profiles during the establishment of CHK-Q (Chinese hamster kidney-derived cell line) and derivative cells

ABSTRACT: CHK-Q cell line was established from primary culture of Chinese hamster kidney tissues by repeated passages. DNA microarray analysis for chasing the variation in gene expression profile was performed for CHK cells during the culture process leading to immortalization and adaptation to serum-free and suspension conditions.

ORGANISM(S): Cricetulus griseus

SUBMITTER: Masamichi Kamihira

PROVIDER: E-MTAB-11298 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Publications

Novel cell lines derived from Chinese hamster kidney tissue.

Kawabe Yoshinori Y Kamihira Masamichi M

PloS one 20220331 3

Immortalized kidney cell lines are widely used in basic and applied research such as cell permeability tests and drug screening. Although many cell lines have been established from kidney tissues, the immortalization process has not been clarified in these cell lines. In this study, we analyzed the phenotypic changes that occurred during the immortalization of kidney cells derived from Chinese hamster tissue in terms of karyotype and gene expression profiles. In the newly established cell line, ...[more]

PMID: 35358245

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Dataset Information

Gene expression profiles during the establishment of CHK-Q (Chinese hamster kidney-derived cell line) and derivative cells

Publications

Novel cell lines derived from Chinese hamster kidney tissue.

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