Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
DISEASE(S): mock infection
SUBMITTER: Giulio Superti-Furga
PROVIDER: E-MTAB-1148 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Nature 20120701 7408
Viruses must enter host cells to replicate, assemble and propagate. Because of the restricted size of their genomes, viruses have had to evolve efficient ways of exploiting host cell processes to promote their own life cycles and also to escape host immune defence mechanisms. Many viral open reading frames (viORFs) with immune-modulating functions essential for productive viral growth have been identified across a range of viral classes. However, there has been no comprehensive study to identify ...[more]