Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: Gijsbert van Nierop
PROVIDER: E-MTAB-12161 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Aguilar-Bretones Muriel M Westerhuis Brenda M BM Raadsen Matthijs P MP de Bruin Erwin E Chandler Felicity D FD Okba Nisreen Ma NM Haagmans Bart L BL Langerak Thomas T Endeman Henrik H van den Akker Johannes Pc JP Gommers Diederik Ampj DA van Gorp Eric Cm EC GeurtsvanKessel Corine H CH de Vries Rory D RD Fouchier Ron Am RA Rockx Barry Hg BH Koopmans Marion Pg MP van Nierop Gijsbert P GP
The Journal of clinical investigation 20211101 21
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the cause of coronavirus disease 2019 (COVID-19). Little is known about the interplay between preexisting immunity to endemic seasonal coronaviruses and the development of a SARS-CoV-2-specific IgG response. We investigated the kinetics, breadth, magnitude, and level of cross-reactivity of IgG antibodies against SARS-CoV-2 and heterologous seasonal and epidemic coronaviruses at the clonal level in patients with mild or severe COVID- ...[more]