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RNA-Seq analysis of mouse heart tissue

ABSTRACT: The purpose of the experiment is to assess the genes expression changes in the heart in response to transverse aortic constriction (TAC)-induced pressure overload, and to identify the genes which are involved in the pathogenesis of heart failure induced by hypertension; thereafter examining the individual gene function in the heart and discovering the novel drug targets to prevent heart failure. Wild-type C57 mice were subjected to transverse aortic constriction (TAC) for 12 weeks (sham as the control, Con). The hearts were collected and snap frozen for the following experiments.

INSTRUMENT(S): Illumina HiSeq 4000

ORGANISM(S): Mus musculus

SUBMITTER: Ian Donaldson

PROVIDER: E-MTAB-12979 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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