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Coupled single-cell RNA, TCR, and barcoded pMHC multimer sequencing, from virus-specific PBMC T-cells

ABSTRACT: Virus-specific CD8 T cells from PBMCs of healthy donors and hepatitis patients were enriched for recognition of a panel of feature barcode-labeled pMHC multimers. The phenotypic description was made using gene expression and TCRseq. Samples were pooled and sequenced on the same 10x Genomics sequencing chip and deconvoluted using ADT HashTag antibodies,

INSTRUMENT(S): Illumina NovaSeq 6000

ORGANISM(S): Homo sapiens

SUBMITTER: Grigorii Nos

PROVIDER: E-MTAB-13758 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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