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Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

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RNA-seq data set of EGFR mutant human non-small cell lung cancer cell lines PC9, HCC827, HCC4006 after NF2 knockout, YAP1 or WWTR1 overexpression or osimertinib treatment

ABSTRACT: Experiment was designed to study the effect of Hippo pathway on osimertinib resistance in non-small cell lung cancer cell lines. The specific comparisons investigated were: PC-9: NTC vs NF2 KO, EV vs YAP1 OE, EV vs WWTR1 OE, EV DMSO treated vs EV osimertinib treated HCC827: NTC vs NF2 KO, EV vs YAP1 OE, EV vs WWTR1 OE,EV DMSO treated vs EV osimertinib treated HCC4006: NTC vs NF2 KO, EV vs YAP1 OE, EV vs WWTR1 OE, EV DMSO treated vs EV osimertinib treated

INSTRUMENT(S): n/a, Illumina NovaSeq 6000, QIAcube HT

ORGANISM(S): Homo sapiens

SUBMITTER: Daniel Barrell

PROVIDER: E-MTAB-13831 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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