Unknown,Transcriptomics,Genomics,Proteomics

Dataset Information

Transcription profiling by array of 784 non-responsive mutants out of 1,484 budding yeast deletion mutants

ABSTRACT: This dataset consists of 784 non-responsive mutants (three or less significant mRNA expression changes as a result of the deletion) from a gene expression profile compendium of 1,484 deletion mutants that have a role or are implicated in mRNA transcription regulation, mRNA turnover, signaling or are located in the nucleus.

ORGANISM(S): Saccharomyces cerevisiae

SUBMITTER: Patrick Kemmeren

PROVIDER: E-MTAB-1384 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

ACCESS DATA

Publications

Large-scale genetic perturbations reveal regulatory networks and an abundance of gene-specific repressors.

Kemmeren Patrick P Sameith Katrin K van de Pasch Loes A L LA Benschop Joris J JJ Lenstra Tineke L TL Margaritis Thanasis T O'Duibhir Eoghan E Apweiler Eva E van Wageningen Sake S Ko Cheuk W CW van Heesch Sebastiaan S Kashani Mehdi M MM Ampatziadis-Michailidis Giannis G Brok Mariel O MO Brabers Nathalie A C H NA Miles Anthony J AJ Bouwmeester Diane D van Hooff Sander R SR van Bakel Harm H Sluiters Erik E Bakker Linda V LV Snel Berend B Lijnzaad Philip P van Leenen Dik D Groot Koerkamp Marian J A MJ Holstege Frank C P FC

Cell 20140401 3

To understand regulatory systems, it would be useful to uniformly determine how different components contribute to the expression of all other genes. We therefore monitored mRNA expression genome-wide, for individual deletions of one-quarter of yeast genes, focusing on (putative) regulators. The resulting genetic perturbation signatures reflect many different properties. These include the architecture of protein complexes and pathways, identification of expression changes compatible with viabili ...[more]

PMID: 24766815

Dataset Information

Transcription profiling by array of 784 non-responsive mutants out of 1,484 budding yeast deletion mutants

Publications

Large-scale genetic perturbations reveal regulatory networks and an abundance of gene-specific repressors.

Similar Datasets

OmicsDI is part of the ELIXIR infrastructure

Tweets

Similar Datasets

Compendium of deletion mutant gene expression profiles, 784 non-responsive mutants [hs1990]
2014-04-24 | GSE42526 | GEO

Transcription profiling by array of 700 responsive mutants out of 1,484 budding yeast deletion mutants
2014-04-24 | E-MTAB-1383 | biostudies-arrayexpress

Compendium of deletion mutant gene expression profiles, 700 responsive mutants [hs1991]
2014-04-24 | GSE42527 | GEO

Compendium of deletion mutant gene expression profiles, 784 non-responsive mutants [hs1990]
2014-04-24 | E-GEOD-42526 | biostudies-arrayexpress

Compendium of deletion mutant gene expression profiles, 700 responsive mutants [hs1991]
2014-04-24 | E-GEOD-42527 | biostudies-arrayexpress

Transcription profiling by array of 376 budding yeast wildtypes for assessing day-to-day variance
2014-04-24 | E-MTAB-1461 | biostudies-arrayexpress

Expression profiling of 376 wildtypes to assess day-to-day variance
2014-04-24 | GSE45115 | GEO

proteomic analysis of deletion mutants in Cronobacter sakazakii BAA-894
2023-03-07 | PXD040672 |