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Metabolomics,Unknown,Transcriptomics,Genomics,Proteomics

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Effects of the Sox17∆50/GFP mutation on SOX17 function in mouse embryonic liver development

ABSTRACT: To determine the role of specific cis-regulatory elements within the Sox17 endoderm-preferential TSS2 promoter, we generated Sox17∆50 mutant animals, crossed them to a Sox17GFPCre (a Sox17 null allele), and surveyed how this mutation affected Sox17 expression. Livers were isolated from E12.5 Sox17∆50/GFPCRe compound heterozygous and Sox17+/+ embryos (n = 4 of each genotype), RNA isolated, and bulk RNA-Seq performed.

INSTRUMENT(S): Illumina NovaSeq 6000

ORGANISM(S): Mus musculus

SUBMITTER: Jean-Philippe Cartailler

PROVIDER: E-MTAB-13983 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress

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Effects of the Sox17 ∆50 mutation on SOX17 function in mouse embryonic liver development

2024-10-31 | E-MTAB-13982 | biostudies-arrayexpress

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Effects of the Sox17∆50 mutation on SOX17 function in mouse embryonic biliary development

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