Ontology highlight
ABSTRACT:
INSTRUMENT(S): Illumina HiSeq 2000
ORGANISM(S): Tribolium castaneum
SUBMITTER: Rahul Hepat
PROVIDER: E-MTAB-1835 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Hepat Rahul R Song Ji-Joon JJ Lee Daeweon D Kim Yonggyun Y
Journal of virology 20130807 20
A viral histone H4 (CpBV-H4) is encoded in a polydnavirus, Cotesia plutellae bracovirus. Its predicted amino acid sequence is highly homologous to that of host insect histone H4 except for an extended N-terminal tail containing 38 amino acids with nine lysine residues. Its expression induces an immunosuppression of target insects by suppressing immune-associated genes, presumably through an epigenetic control. This study analyzed its molecular interaction with eukaryotic host nucleosomes and sub ...[more]