Ontology highlight
ABSTRACT:
INSTRUMENT(S): Illumina HiSeq 2000
ORGANISM(S): Mus musculus
SUBMITTER: Claudia Kutter
PROVIDER: E-MTAB-2328 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Schmitt Bianca M BM Rudolph Konrad L M KL Karagianni Panagiota P Fonseca Nuno A NA White Robert J RJ Talianidis Iannis I Odom Duncan T DT Marioni John C JC Kutter Claudia C
Genome research 20140813 11
The genetic code is an abstraction of how mRNA codons and tRNA anticodons molecularly interact during protein synthesis; the stability and regulation of this interaction remains largely unexplored. Here, we characterized the expression of mRNA and tRNA genes quantitatively at multiple time points in two developing mouse tissues. We discovered that mRNA codon pools are highly stable over development and simply reflect the genomic background; in contrast, precise regulation of tRNA gene families i ...[more]