Ontology highlight
ABSTRACT:
INSTRUMENT(S): Agilent DNA Microarray Scanner
ORGANISM(S): Homo sapiens
SUBMITTER: Jan Smetana
PROVIDER: E-MTAB-3577 | biostudies-arrayexpress |
REPOSITORIES: biostudies-arrayexpress
Neoplasma 20140101 1
Multiple myeloma (MM) is an incurable malignant disease of the terminal developmental stage of B-lymphocytes. While genetic heterogeneity of MM is widely described, little is known about its genetic basis as well as primary damage during plasma cells (PC) development. In this study, we focused on genome-wide screening of DNA copy number changes using oligonucleotide-based array-CGH together with I-FISH of the IgH locus rearrangements in pair samples of bone marrow B-cells (CD19+) and CD138+ PC f ...[more]